Wednesday 20th October 2010| 17:00 | Registration | | 18:00 | Opening Address
Professor Richard Carter, The University of Edinburgh, UK | | 18:45 | Poster viewing | | 20:00 | End of Day 1 |
Thursday 21st October 2010| 08:00 | Registration & Coffee
| | 08:30 | Keynote Address
Epidemiology of malaria resistance or Artemisinin: resistance or temporary tolerance
Carol Sibley, University of Washington, USA |
Session 1: Advances in understanding parasite biology and host-parasite interactions that are relevant to disease and treatment
Chair: Kiaran Kirk, The Australian National University, Australia
| 09:00 | Invasion and modification of the host erythrocyte
Brendan Crabb, Burnet Institute, Australia |
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| 09:20 | Stepwise dissection of Plasmodium falciparum merozoite invasion of the human erythrocyte
Jake Baum, Walter and Eliza Hall Institute, Australia | | 09:35 | Liver stage malaria
Maria M. Mota, Institute of Molecular Medicine, Portugal | | 09:55 | Transporters of parasites as drug targets: tempting but underexploited
Henry Staines, St George's University of London, UK | | 10:15 | Polyamine uptake in the malaria parasite, Plasmodium falciparum, is dependent on the parasite’s membrane potential
Braam Louw, University of Pretoria, South Africa | | 10:30 | A comprehensive survey of protein palmitoylation in late blood-stage Plasmodium falciparum
Matthew L.Jones, Wellcome Trust Sanger Institute, UK |
Session 2: Assimilating genome-wide analyses of parasites to provide new tools for vaccines and drug discovery projects, as well as understanding the mechanisms of resistance
Chair: Stephen Ward, Liverpool School of Tropical Medicine, UK | 11:15 | Metabolomics approaches to understanding host parasite interaction
Kellen Olszewski, Princeton University, USA | | 11:35 | Systematic gene knockout in P. berghei for analysis gene functions. Current status, how to extrapolate to human parasites.
Olliver Billker, The Wellcome Trust Sanger Institute, UK | | 11:55 | Understanding Plasmodium sexual stage and zygote development and their translation
Andy Waters, University of Glasgow UK |
| 12:15 | Investigating transcriptional regulation of Plasmodium falciparum upon drug perturbation
Tharina van Brummelenssion, CSIR, South Africa | | 12:30 | Ancient out-of-Africa migration of Plasmodium falciparum along with modern humans
Kazuyuki Tanabe, Osaka University, Japan | | 12:45 | A library of functional recombinant Plasmodium falciparum merozoite surface proteins
Cecile Wright-Crosnier, Wellcome Trust Sanger Institute |
Session 3: Vector biology: New approaches to vector control of plasmodium parasites
Chair: Hilary Hurd, Keele University, School of Life Sciences | 14:00 | Push-pull strategies for vector control
Willem Takken, Wageningen University, Netherlands |
| 14:20 | Studies on the breeding swarms of Anopheles gambiae complex in malaria control perspective
Benoît S. Assogba, Benin | | 14:35 | Larval time-to-hatch and insecticide resistance in the major malaria vector Anopheles gambiae from Ghana
Basil Brooke, National Institute for Communicable Diseases, Johannesburg | | 14:50 | Characterization and comparative sequence analyzes of GABA receptor gene in Asian main malaria mosquito, Anopheles stephensi
Navid Dinparast Djadid, Pasteur Institute of Iran, Iran | | 15:05 | Sugar-fermenting yeast as an organic source of carbon dioxide to attract the malaria mosquito Anopheles gambiae s.s.
Renate Smallegange, Wageningen University, The Netherlands | | 15:20 | Intra-host dynamics of mixed species malaria parasite infections in mice and mosquitoes
Richard Culleton, Nagasaki University, Japan | | 15:35 | The role of LCCL proteins in malaria transmission
Sadia Saeed, London School of Hygiene & Tropical Medicine, UK |
Session 4: Emerging parasites: Recently discovered knowlesi in humans that is providing new insights into pathophysiology of malarial infections
Chair: David Sullivan, Johns Hopkins University, USA | 16:05 | Insights from monkey malaria that can change thinking about human infections
Janet Cox-Singh, St George's University of London, UK | | 16:25 | P. ovale
Colin Sutherland, London School of Hygiene & Tropical Medicine, UK | | 16:55 | P vivax: The Duffy dogma revisited
Peter Zimmerman, Case Western Reserve University, USA |
| 17:15 | Adaptation of in vitro cytoadherence assay to Plasmodium knowlesi field isolates
Farrah A Fatih, St George’s University of London, UK | | 17:30 | Origin of the human malaria parasite Plasmodium falciparum in gorillas
Julian C Rayner, Wellcome Trust Sanger Institute, UK | | 17:45 | Wild chimpanzees are infected with homologous types of human malaria
Marco Kaiser, Robert Koch-Institute, Germany |
| 18:00 | Poster Viewing | | 19:00 | End of Day 2 | | 19:30 | Coaches depart for dinner | | 20:00 | Conference Dinner at Dynamic Earth |
Friday 22nd October 2010Session 5: Revisiting the sequestration and cytokine/mediator models for pathogenesis
Chair: Sanjeev Krishna, St George’s University of London, UK | 08:30 | Coffee | | 09:00 | Var2CSA binding
Ali Salanti, University of Copenhagen, Denmark | | 09:20 | Retinopathy and microcirculation in adult severe malaria
Richard J Maude, Mahidol -Oxford Tropical Medicine Research Unit, Thailand |
| 09:40 | Variant surface antigens in cerebral malaria: distinct from others and similar to each other?
Agnès Aubouy, Institut de Recherche pour le Développement (IRD), France | | 09:55 | Transfer of 4-hydroxynonenal, a inhibitory hemozoin (HZ) product, from HZ or HZ-laden phagocytes to developing human erythroid cells. A model for erythropoiesis inhibition in malaria anemia
Paolo Arese, University of Torino Medical School, Italy |
| 10:10 | Molecular Epidemiology of Force of Infection in malaria
Ingrid Felger, Swiss Tropical and Public Health Institute, Switzerland | | 10:25 | Immunopathology and Dexamethasone Therapy in a new Model for Malaria-Associated Acute Respiratory Distress Syndrome
Philippe E. Van den Steen, University of Leuven, Belgium | | 10:40 | Coffee |
Session 6: Drug discovery - renewed vision and role in malaria control and elimination
Chair: Henri Vial, CNRS University of Montpellier | 11:10 | Keynote Address
New drug treatments in the portfolio
Tim Wells, Medicines for Malaria Venture (MMV), Switzerland | | 11:40 | Basic biology
Stephen Ward, Liverpool School of Tropical Medicine, UK | | 12:00 | Refreshed approaches to the therapy of malaria – the case of natural medicine
Hagai Ginsburg, The Hebrew University of Jerusalem, Israel |
| 12:20 | Progress in the development of Reversed Chloroquine molecules as antimalarial therapy
David H. Peyton, Portland State University, USA | | 12:35 | Identification and characterization of novel Plasmodium falciparum cyclophilins and their roles in the antimalarial actions of cyclosporin A and derivatives
Angus Bell, Trinity College Dublin, Ireland | | 12:50 | Development of a Novel Drug for Uncomplicated Malaria Targeting the Mitochondrial NADH: Quinone Oxidoreductase
Giancarlo Biagini, Liverpool School of Tropical Medicine, UK | | 13:05 | Antimalarial activity of ulein and a proof of its action on the Plasmodium falciparum digestive vacuole
Alaíde Braga, Universidade Federal de Minas Gerais, Brazil | | 13:25 | Identification of genetic markers of resistance to Artemisinin Combination Therapy in the rodent model Plasmodium chabaudi
Louise Rodrigues, Instituto Instituto de Higiene e Medicina Tropical Universidade Nova de Lisboa, Portugal |
Session 7: Immunology and vaccine development
Chair: Alister Craig, Liverpool School of Tropical Medicine UK | 14:25 | Sanaria malaria extraction through vaccination
Dr. Peter Billingsley, Sanaria, USA |
| 14:45 | Viral vectored transmission blocking vaccines against Plasmodium falciparum
Melissa Kapulu, University of Oxford, UK | | 15:00 | Impact of protective haemoglobins C and S on P. falciparum malaria transmission in endemic area
Louis-Clément Gouagna, Institut de Recherche pour le Développement, France | | 15:15 | Complete abrogation of sporozoite-induced sterile immunity by blood stage parasites of homologous and heterologous malaria species
Megumi Inoue, Nagasaki University, Japan | | 15:30 | Predicted impact of mosquito-stage transmission-blocking vaccines using an ensemble of microsimulations
Aurelio Di Pasquale, Swiss Tropical and Public Health Institute, Switzerland | | 15:45 | A micro-bead device to explore Plasmodium falciparum-infected, spherocytic or aged red blood cells prone to mechanical retention by spleen endothelial slits
Innocent Safeukui, Institut Pasteur, France |
Session 8: Disease Control: Vector control options are constantly evolving, whether by pesticide, sterile insect technique or biological control. What else is on the horizon?
Chair: Marcel Hommel, University of Liverpool, Editor-in-Chief, Malaria Journal, UK | 16:25 | The elimination roadmap
Marcel Tanner, Swiss Tropical and Public Health Institute, Switzerland | | 16:45 | Integrated vector management (IVM): from concept to practice
Henk van den Berg, Laboratory of Entomology, Wageningen University, The Netherlands |
| 17:05 | Modeling the effects of vector control interventions in reducing malaria transmission, morbidity and mortality
Konstantina Boutsika, Swiss Tropical & Public Health Institute, Switzerland | | 17:20 | Controlling malaria in Niger with bednets: how to take the Big Picture?
Jean-Bernard Duchemin, Institut Pasteur, France | | 17:35 | Household size explains successful malaria eradication
Lena Hulden, University of Helsinki, Finland | | 17:40 | What has been the contribution of the first Global Fund grant (2003-2006) to malaria control and health system strengthening in Timor-Leste?
Joao S Martins, University of New South Wales, Australia |
| 17:55 | Closing remarks | | 18:05 | Close of Day 3 |
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